Archive

Review Article
The success of stem cell transplantations and the potential post-transplantation complications may be dependent, among other factors, on the capacity of the recipient and the transplanted cells to repair DNA damage
DOI: 10.7750/BioDiscovery.2016.19.1
Review Article
An old wives' tale. Reproductive outcomes in pregnant women aged 35 or older: the role of individual repair capacity
DOI: 10.7750/BioDiscovery.2015.18.2
Short Communication
A de novo microdeletion 2p24.3-25.1 identified in a girl with global development delay
DOI: 10.7750/BioDiscovery.2015.18.1
Research Article
Blood-Based Gene Expression in children with Autism spectrum disorder
DOI: 10.7750/BioDiscovery.2015.17.2
Review Article
APOE4, oxidative stress and decreased repair capacity - a no-brainer. Faulty lipid metabolism and increased levels of oxidative damage may be risk factors in the pathogenesis of late-onset dementia
DOI: 10.7750/BioDiscovery.2015.17.1
Review Article
Human pluripotent stem-cell-derived cardiomyocytes in cardiovascular drug discovery and development
DOI: 10.7750/BioDiscovery.2015.16.1
Commentary
Small molecules and human cardiomyogenesis: Is there a bottleneck in current research?
DOI: 10.7750/BioDiscovery.2015.15.2
Research Article
NRF2 inhibition causes repression of ATM and ATR expression leading to aberrant DNA Damage Response
DOI: 10.7750/BioDiscovery.2015.15.1
Review Article
We heart cultured hearts. A comparative review of methodologies for targeted differentiation and maintenance of cardiomyocytes derived from pluripotent and multipotent stem cells
DOI: 10.7750/BioDiscovery.2014.14.2
Short Communication
Multiplexed heat shock protein microarray as a screening platform for the selection of novel drug compounds
DOI: 10.7750/BioDiscovery.2014.14.1
Review Article
DNA repair systems
DOI: 10.7750/BioDiscovery.2014.13.2
Review Article
DNA damage and the circadian clock
DOI: 10.7750/BioDiscovery.2014.13.1
Review Article
DNA repair and carcinogenesis
DOI: 10.7750/BioDiscovery.2014.12.1
Review Article
Individual capacity for detoxification of genotoxic compounds and repair of DNA damage. Commonly used methods for assessment of capacity for DNA repair
DOI: 10.7750/BioDiscovery.2014.11.2
Review Article
DNA damage and mutation. Types of DNA damage
DOI: 10.7750/BioDiscovery.2014.11.1
Monograph
From Roscovitine to CYC202 to Seliciclib – from bench to bedside: discovery and development
DOI: 10.7750/BioDiscovery.2013.10.1
Research Article
Progesterone significantly enhances the mobility of boar spermatozoa
DOI: 10.7750/BioDiscovery.2013.9.5
Research Article
Reverse engineering of drug induced DNA damage response signalling pathway reveals dual outcomes of ATM kinase inhibition
DOI: 10.7750/BioDiscovery.2013.9.4
Research Article
The alternate GNB3 splice variant, Gβ3s, exhibits an altered signalling response to EGF stimulation, which leads to enhanced cell migration
DOI: 10.7750/BioDiscovery.2013.9.3
Research Article
Changes in the connective tissue element of the thyroid gland in normal and recurrent euthyroid goiter
DOI: 10.7750/BioDiscovery.2013.9.1
Review Article
Evolution of Conformational Disorder & Diversity of the P53 Interactome
DOI: 10.7750/BioDiscovery.2013.8.5
Review Article
Small Molecule Inhibitors of MDM2-p53 and MDMX-p53 Interactions as New Cancer Therapeutics
DOI: 10.7750/BioDiscovery.2013.8.4
Review Article
Distinct target genes and effector processes appear to be critical for p53-activated responses to acute DNA damage versus p53-mediated tumour suppression
DOI: 10.7750/BioDiscovery.2013.8.3
Review Article
Modulation of immune responses by the tumor suppressor p53
DOI: 10.7750/BioDiscovery.2013.8.2
Review Article
Switching on p53: an essential role for protein phosphorylation?
DOI: 10.7750/BioDiscovery.2013.8.1
Research Article
Modelling c-Abl Signalling in Activated Neutrophils: The Anti-inflammatory Effect of Seliciclib
DOI: 10.7750/BioDiscovery.2013.7.4
Research Article
Herpetofauna in the city of Blagoevgrad, south-western Bulgaria
DOI: 10.7750/BioDiscovery.2013.7.3
Review Article
Skeletal muscle: novel and intriguing characteristics as a secretory organ
DOI: 10.7750/BioDiscovery.2013.7.2
Research Article
Chromosome rearrangements in sublines of human embryonic stem cell lines hESM01 and hESM03
DOI: 10.7750/BioDiscovery.2013.7.1
Review Article
Advocating the need of a systems biology approach for personalised prognosis and treatment of B-CLL patients
DOI: 10.7750/BioDiscovery.2012.6.4
News and Views
Bringing together all aspects of cancer research, prevention and treatment. A report from the 8th NCRI Cancer Conference
DOI: 10.7750/BioDiscovery.2012.6.3
Research Article
The aromatase inhibitor letrozole enhances the effect of doxorubicin and docetaxel in an MCF7 cell line model
DOI: 10.7750/BioDiscovery.2012.6.2
Commentary
Primed for the kill: occupying Bcl-2 to target death in acute myeloid leukaemia
DOI: 10.7750/BioDiscovery.2012.6.1
Review Article
ATM in focus: A damage sensor and cancer target
DOI: 10.7750/BioDiscovery.2012.5.1
Commentary
To see an interphase chromosome or: How a disease can be associated with specific nuclear genome organization
DOI: 10.7750/BioDiscovery.2012.4.5
Commentary
What can systems pharmacology contribute to drug development? Disease modelling as a predictive tool
DOI: 10.7750/BioDiscovery.2012.4.4
Research Article
Prevalence of oral lesions in HIV infected adult population of Mangalore, Karnataka, India
DOI: 10.7750/BioDiscovery.2012.4.3
Research Article
Does positioning of chromosomes 8 and 21 in interphase drive t(8;21) in acute myelogenous leukemia?
DOI: 10.7750/BioDiscovery.2012.4.2
Short Communication
In vitro assessment of the cytotoxic effects of novel RGD analogues
DOI: 10.7750/BioDiscovery.2012.4.1
News and Views
The dark side of light. Light pollution kills leatherback turtle hatchlings
DOI: 10.7750/BioDiscovery.2012.3.4
Research Article
Lifestyle characteristics and dietary impact on plasma concentrations of beta-carotene and retinol
DOI: 10.7750/BioDiscovery.2012.3.3
Research Article
The Apoe -/- Mouse PhysioLab ® Platform: A Validated Physiologically-based Mathematical Model of Atherosclerotic Plaque Progression in the Apoe -/- Mouse
DOI: 10.7750/BioDiscovery.2012.3.2
Review Article
Of mice and men – differential mechanisms of maintaining the undifferentiated state in mESC and hESC
DOI: 10.7750/BioDiscovery.2012.3.1
Hypotheses
Parallel Researching with Online Collaboration (PROC), a new cost effective model for multicentre multinational research
DOI: 10.7750/BioDiscovery.2012.2.3
Research Article
Viability of unstimulated lymphocytes exposed to extremely low frequency electromagnetic fields is dependent on intensity
DOI: 10.7750/BioDiscovery.2012.2.2
Research Article
Up-regulation of Gr1 + CD11b + cell population in the spleen of NaClO-administered mice works to repair skin wounds
DOI: 10.7750/BioDiscovery.2012.2.1
Cover Story
Man of Science: Celebrating Professor Sir David Lane’s 60th anniversary
DOI: 10.7750/BioDiscovery.2012.1.5
Research Article
Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype
DOI: 10.7750/BioDiscovery.2012.1.4
Review Article
Targeting ATM pathway for therapeutic intervention in cancer
DOI: 10.7750/BioDiscovery.2012.1.3
Research Article
Bisphosphonate-related osteonecrosis of the jaws: Report of two cases with breast cancer, a dental concern and review of the literature
DOI: 10.7750/BioDiscovery.2012.1.2
Research Article
Modelling malignant progression with a finite state machine supports a two checkpoint theory of cancer
DOI: 10.7750/BioDiscovery.2012.1.1